First in Assam or First Assamese:
| First Ambedkar Awardee of Assam | Chetana Das (2000) |
| First Arjuna Awardee of Assam | Bhogeswar Barua(1990) |
| First Assam Valley Literary Award winner of Assam | Bhabendranath Saikia (1990) |
| First Assamese movie | Joymoti |
| First Assamese colour movie | Bhaiti (1972) |
| First Assamese Lexicographer | Jaduram Dekabaruah (1839) |
| First Assamese Governor | Bishnuram Medhi (Madras, 8 Jan 1957 to 4 April, 1964) |
| First Bharat Ratna Awardee of Assam | Gopinath Bordoloi (1999, Posthumously) |
| First of Bibliography of Assam | Asomiya Puthir Talika (Devananda Bharali, 1912) |
| First Bismilla Khan Award winner of Assam | Sukracharya Rabha (2010) |
| First Assamese book that received Sahitya Academy Award | Bonphool (Jatindranath Duwarah, 1955) |
| First bridge over the river Brahmaputra | Saraighat (1962), Guwahati |
| First Cabinet Minister of Union Cabinet from Assam | Fakharuddin Ali Ahmed |
| First Chief Justice of High Court of Assam | Haliram Deka |
| First Justice of Supreme Court from Assam | Parvati Kumar Goswami |
| First Co-Operative of Assam | Shillong (Shillong Co-operative Town Bank, estd.- 13th September 1904) |
| First Chief Minister of Assam | Gopinath Bordoloi (1938-1939) |
| First College in Assam | Cotton College (1901) |
| First Daily Newspaper in Assam | Dainik Batori (1935) |
| First Dictionary in Assam | Asomiya aru Engraji Abhidhan (Miles Bronson, 1867) |
| First Doctor of Philosophy (PhD) from London University from Assam | Maidul Islam Bora |
| First D Lit of London University from Assam | Surjya Kumar Bhuyan |
| First English News Paper in Assam | Assam Tribune (1946) |
| First Film Studio in Assam | Jyoti Chitraban (1961) |
| First Assamese Children’s Novel | Patalpuri (Hargovinda Sharma) |
| First Gold Medalist in Asian Games from Assam | Bhogeswar Baruah (1966) |
| First Graduate from Assam | Anandoram Baruah |
| First Grammar book of Assam | Grammar of the Assamese Language (William Robinson, 1839) |
| First Historical Novel of Assam | Bhanumati (Padmanath Gohain Baruah, 1890) |
| First IAS from Assam | Anandoram Baruah |
| First Institute for Higher Education in Assam | Cotton College |
| First Film Maker of Assam | Jyoti Prasad Agarwala |
| First recipient of Jnanpeeth Award from Assam | Dr Birendra Kumar Battacharya, (Mrityunjay, 1979) |
| First Jnanpeeth award winning book of Assam | Mrityunjay (Dr Birendra Kumar Bhattacharya, 1979) |
| First Woman Jnanpeeth Awardee from Assam | Mamoni Raisom Goswami (2000) |
| First Lok Adalot in Assam | Hajo |
| First Modern Play of Assam | Ram Navami (Gunabhiram Baruah, 1857) |
| First Medical School in Assam | Berry White Medical School (1902), Dibrugarh |
| First Medical College in Assam | Assam Medical College, Dibrugarh (1947) |
| First Mental Hospital in Assam | Tezpur Mental Hospital (original namtu beleg kintu Sambhu) |
| First Novel on Tribal life of Assam | Miri Jiyori (Rajanikanta Bordoloi, 1894) |
| First Novel that received Sahitya Academy Award of Assam | Yaruyingam (Dr Birendra Kr Bhattacharya, 1961) |
| First President of India from Assam | Fakaruddin Ali Ahmed (24 August 1974-11 February 1977) |
| First Padma Bhusan Awardee from Assam | Nabakanta Baruah (1976) |
| First Padma Shri Awardee from Assam | Parveen Sultana (1976) |
| First play from Assam to be broadcasted over AIR | Been Boragi (Prafulla Chandra Baruah, 1935) |
| First Printed book of Assam | Dharam Pustak (Atmaram Sharma, 1813) |
| First Printing Press in Assam | Mission Press, Sivasagar |
| First Prose of Assam | Katha Geeta (Bhattadev) |
| First Radio Station in Assam | Guwahati and Shillong (estd 1 July 1948) |
| First Rajiv Gandhi Sadvabana Award winner from Assam | Hiteswar Saikia (1955) |
| First Romantic poetry of Assam | Bon Kuwori (Chandra Kumar Agarwala) |
| First RTI Awardee from Assam | Akhil Gogoi (2010) |
| First Sahitya Academy Awardee of Assam | Jatindranath Duwarah ( Bonphool, 1955) |
| First Sangeet Natak Academy of Assam | Prabhat Sharma, Arun Sharma |
| First short story collection of Assam | Surabhi (Lakshminath Bezbaruah, 1909) |
| First Shri Manta Shankardev Award winner from Assam | Kirtinath Hazarika (1986) |
| First Sonnet Assamese | Priyotomar Sithi |
| State bird of Assam | Deo Hanh |
| State flower of Assam | Orchid (Fox tail) |
| State Emblem of Assam | One-horned Indian Rhino |
| State Animal of Assam | One-horned Indian Rhino |
| First Thesis in Assamese Language | Assamese: Its formation and Development ( Dr Banikanta Kakati, 1940) |
| First University in Assam | Gauhati University |
| First High Court in Assam | Gauhati High Court (1948) Guwahati |
| First Woman Doctor from Assam | Dr Rajaniprabha Saikia |
| First Woman Graduate from Assam | Sukhalata Dowarah, Sudhalata Dowarah |
| First Woman Minister in the Union Cabinet from Assam | Renukadevi Barkotoky |
| First Woman Justice of High Court of Assam | Meera Sarma |
| First Woman ACS of Assam | Suchibrata Raichowdhury |
| First Woman IAS from Assam | Parul Das |
| First Woman Chief Minister of Assam | Saiyeda Anowara Taimur (1980-1981) |
| First Assamese International award winner Film | Sagaralai Bahudoor ( Directed by Jahnu Baruah) |